HIN BONNER SCHÖFFENBRIEF VOM 10. M AI 1513

Dmd051912 1505..1513

The cytosolic sulfotransferases (SULTs) catalyze the sulfate conjugation of nucleophilic substrates, and the cofactor for sulfonation, 39-phosphoadenosine-59-phosphosulfate (PAPS), is biosynthesized from sulfate and ATP. The phenotype of male knockout mice for the NaS1 sodium sulfate cotransporter includes hyposulfatemia and increased hepatic expression of mouse cytoplasmic sulfotransferase Sul...

PHYSIOLOG Y: BONNER AND BONNER ASCORBIC ACID AND THE GROWTH OF PLANT EMBRYOS By JAMES BONNER AND DAVID BONNER

John Bonner

John Bonner started working on cellular slime molds in 1940 as an undergraduate at Harvard University, and resumed those studies there as a graduate student after the 2nd World War, finishing his PhD in 1947. His first job was in biology at Princeton University, where he has remained ever since: from assistant professor to professor emeritus. He continues to pursue both his laboratory research ...

Jcb_201704017 1513..1516

1513 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 216 No. 6 1513–1515 https://doi.org/10.1083/jcb.201704017 Ionic homeostasis and ion transport are essential for all life forms on Earth. Well defined concentrations of key ions, most commonly Na+, K+, Cl−, Ca2+, and H+, are maintained not only in the cytoplasm and extracellular space but also inside subcellular organelles. Ionic gr...

Dmd058354 1508..1513

Orally administered drugs may be metabolized by intestinal microbial enzymes before absorption into the blood. Accordingly, coadministration of drugs affecting the metabolic activities of gut microbes (e.g., antibiotics) may lead to drug-drug interactions (DDI). In this study, gut microbiota-mediated DDI were investigated by studying the pharmacokinetics of lovastatin in antibiotic-treated rats...